Concepedia

MRS2500 [2-Iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y1 Receptor with Strong Antithrombotic Activity in Mice

Béatrice Hechler, Christelle Nonne, Eun Joo Roh, Marco Cattaneo, Jean‐Pierre Cazenave, François Lanza, Kenneth A. Jacobson, Christian Gachet

Journal of Pharmacology and Experimental Therapeutics · 2006 · 149 citations · 24 references

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References

24

Receptors for Purines and Pyrimidines

Geoffrey Burnstock, Alexei Verkhratsky · 2012 · 4K citations

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β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival

Kairbaan Hodivala‐Dilke, Kevin P. McHugh, Dimitrios Α. Tsakiris et al. · Journal of Clinical Investigation · 1999 · 739 citations · Full text

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Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice

Catherine Léon, Béatrice Hechler, Monique Freund et al. · Journal of Clinical Investigation · 1999 · 454 citations · Full text

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Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice

Jean-Etienne Fabre, MyTrang Nguyen, Anne M. Latour et al. · Nature Medicine · 1999 · 440 citations

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Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

Carolyn Foster, Dina M. Prosser, Jacqueline Agans et al. · Journal of Clinical Investigation · 2001 · 414 citations · Full text

, , +17