Acetylation controls Notch3 stability and function in T-cell leukemia

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

G. Lagger, Dónal O’Carroll, Martina Rembold et al. · The EMBO Journal · 2002 · 757 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

Warren S. Pear, Jon C. Aster, Martin Scott et al. · The Journal of Experimental Medicine · 1996 · 712 citations · Full text

Medicine, Molecular Biology, Oncology +13

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

Angela Nebbioso, Nicole Clarke, Emilie Voltz et al. · Nature Medicine · 2004 · 620 citations

Medicine, Oncology, Pharmacology +13

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

Alessandra Insinga, Silvia Monestiroli, Simona Ronzoni et al. · Nature Medicine · 2004 · 515 citations

Life Sciences, Molecular Biology, Oncology +16

Differential Roles of p300 and PCAF Acetyltransferases in Muscle Differentiation

Vittorio Sartorelli, Xiang-Jiao Yang, Yasuo Hamamori et al. · Molecular Cell · 1997 · 418 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +12