Concepedia

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

Angela Nebbioso, Nicole Clarke, Emilie Voltz, Emmanuelle Germain, Concetta Ambrosino, Paola Bontempo, Rosana Álvarez, Ettore Mariano Schiavone, Felicetto Ferrara, Francesco Bresciani,

Nature Medicine · 2004 · 620 citations · 21 references

DOI

Concepts

References

21

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

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Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail et al. · Nature Medicine · 1999 · 2.5K citations

, , +12

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Martin Göttlicher · The EMBO Journal · 2001 · 1.9K citations · Full text

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Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Christopher J. Phiel, Fang Zhang, Eric Yi‐Hsiu Huang et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text

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Histone deacetylase inhibitor selectively induces p21 <sup>WAF1</sup> expression and gene-associated histone acetylation

Victoria M. Richon, Todd W. Sandhoff, Richard A. Rifkind et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations · Full text

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