Heterozygous Germline Mutations in the CBL Tumor-Suppressor Gene Cause a Noonan Syndrome-like Phenotype

Simone Martinelli, Alessandro De Luca, Emilia Stellacci, +23

The American Journal of Human Genetics

Tumor BiologySomatic VariantMendelian DisorderGenetic DisorderGenetics +8

Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

Diana Bellavia, Antonio Francesco Campese, Saula Checquolo, +10

Proceedings of the National Academy of Sciences

Hematological MalignancyT Cell DifferentiationLymphocyte DevelopmentImmune Cell DevelopmentT-regulatory Cell +12

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia

Vivek Kumar, Rocco Palermo, Claudio Talora, +12

Leukemia

Hematological MalignancyCancer ResearchMir-223/fbxw7 AxisMixed-phenotype Acute LeukemiaImmunology +6

Expression of Activated Notch3 in Transgenic Mice Enhances Generation of T Regulatory Cells and Protects against Experimental Autoimmune Diabetes

Emanuela Anastasi, Antonio Francesco Campese, Diana Bellavia, +10

The Journal of Immunology

Pre‐TCR‐triggered ERK signalling‐dependent downregulation of E2A activity in Notch3‐induced T‐cell lymphoma

Claudio Talora, Antonio Francesco Campese, Diana Bellavia, +7

EMBO Reports

Tumor BiologyLymphoid NeoplasiaSignaling PathwayE2a ActivityImmune Regulation +7

PKCθ mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia

María Pía Felli, Alessandra Vacca, Angelica Calce, +11

Oncogene

Signal TransductionSignaling PathwayCell RegulationImmunologyPre-tcr Signaling +3

Opsonin-Deficient Nucleoproteic Corona Endows UnPEGylated Liposomes with Stealth Properties <i>In Vivo</i>

Francesca Giulimondi, Elisabetta Vulpis, Luca Digiacomo, +16

ACS Nano

Acetylation controls Notch3 stability and function in T-cell leukemia

Rocco Palermo, Saula Checquolo, A Giovenco, +13

Oncogene

Hematological MalignancyImmunologyNotch3 StabilityAdult T-cell Leukemia-lymphomaMedicine +2

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression

Giulia Franciosa, Giulia Diluvio, Francesca Del Gaudio, +15

Oncogene

Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL

Maria Pelullo, Roberta Quaranta, Claudio Talora, +12

Neoplasia