Journal of the American Medical Association · 1939 · 60 citations · 1 references
Life SciencesNutritionNutritional SciencesClinical NutritionHuman NutritionNutritional BiochemistryVitamin BiochemistryVitamin ChemistryVitamin MetabolismVitamin PhysiologyWater-soluble VitaminsB VitaminsNutritional Deficiency CorrectionNutritional Deficiency PathologyVitamin B6 Deficiency TreatmentVitamin B6 MetabolismVitamin B6 Status
c Since vitamin B<sub>6</sub>(2-methyl, 3-hydroxy, 4,5-di-[hydroxymethyl] pyridine), one of the water-soluble compounds of the vitamin B complex, is a component of yeast and of liver extract, both of which are effective antipellagric substances, it was thought that perhaps this vitamin also might be important in human nutrition. Clinical studies of the effect of vitamin B<sub>6</sub>on nutritional deficiency diseases were made possible by the recent synthesis<sup>1</sup>of this substance. We<sup>2</sup>described recently the study of a large series of undernourished persons who had clinical evidence of pellagra and beriberi and certain symptoms which are corrected by the
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