Concepedia

Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

Iva Žebrakovská, Martin Máša, Jaroslav Srp, Martin Horn, Kateřina Vávrová, Michael A. Mares

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2011 · 13 citations · 18 references

DOI

Concepts

References

18

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells.

Paul Säftig, Michal Hetman, Wolfgang W. Schmahl et al. · The EMBO Journal · 1995 · 442 citations · Full text

, , +17

Cathepsin D targeted by acid sphingomyelinase‐derived ceramide

Michael Heinrich · The EMBO Journal · 1999 · 367 citations · Full text

, , +14

Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation

Michael Heinrich, Jens Neumeyer, Marten Jakob et al. · Cell Death and Differentiation · 2004 · 330 citations

, , +16

Glycosaminoglycans Facilitate Procathepsin B Activation through Disruption of Propeptide-Mature Enzyme Interactions

Dejan Caglič, Jerica Rozman Pungerčar, Gunnar Pejler et al. · Journal of Biological Chemistry · 2007 · 98 citations · Full text

, , +14

Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation

Madanan Madathiparambil GOPALAKRISHNAN, Hans-Wilhelm Grosch, Silvia Locatelli‐Hoops et al. · Biochemical Journal · 2004 · 76 citations · Full text

, , +11