Probing the substrate specificity for lipases. II. Kinetic and modeling studies on the molecular recognition of 2-arylpropionic esters by Candida rugosa and Rhizomucor miehei lipases

Quantitative analyses of biochemical kinetic resolutions of enantiomers

Ching Shih Chen, Yoshitaka Fujimoto, Gary Girdaukas et al. · Journal of the American Chemical Society · 1982 · 2.6K citations

Natural Sciences, Biochemistry, Chemistry +9

A serine protease triad forms the catalytic centre of a triacylglycerol lipase

Leo Brady, A.M. Brzozowski, Zygmunt S. Derewenda et al. · Nature · 1990 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +16

Structure of human pancreatic lipase

F.K. Winkler, A. D’Arcy, Willi Hunziker · Nature · 1990 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex

A.M. Brzozowski, Urszula Derewenda, Zygmunt S. Derewenda et al. · Nature · 1991 · 1.1K citations

Life Sciences, Biochemistry, Biophysics +14

A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa

Romas J. Kazlauskas, Alexandra N. E. Weissfloch, Aviva T. Rappaport et al. · The Journal of Organic Chemistry · 1991 · 945 citations

Life Sciences, Biochemistry, Chemistry +11