Leo Brady

A serine protease triad forms the catalytic centre of a triacylglycerol lipase

Leo Brady, A.M. Brzozowski, Zygmunt S. Derewenda et al. · Nature · 1990 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +16

Calcium binding in .alpha.-amylases: an x-ray diffraction study at 2.1-.ANG. resolution of two enzymes from Aspergillus

Esper Boel, Leo Brady, A.M. Brzozowski et al. · Biochemistry · 1990 · 318 citations

Life Sciences, Biochemistry, Biology +17

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

Anne‐Catrin Uhlemann, Angus Cameron, Ursula Eckstein‐Ludwig et al. · Nature Structural & Molecular Biology · 2005 · 257 citations

Life Sciences, Biochemistry, Molecular Biology +7

Structure and molecular model refinement of <i>Aspergillus oryzae</i> (TAKA) α-amylase: an application of the simulated-annealing method

H. J. Swift, Leo Brady, Zygmunt S. Derewenda et al. · Acta Crystallographica Section B Structural Science · 1991 · 103 citations

Life Sciences, Biochemistry, Enzymology +15

PRO_SELECT:  Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors

John W. Liebeschuetz, Stuart Jones, Phillip J. Morgan et al. · Journal of Medicinal Chemistry · 2002 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17