Lung Cancer · 2006 · 84 citations · 30 references
MedicineCancer BiologyOncologyCarcinogenesisMolecular OncologyNeoplasiaCancer Cell SignalingHedgehog SignalingLung CancerLung MetastasisMalignant NeoplasmsTumor BiologyCanonical Hedgehog SignalingHedgehog Signaling In ProliferationHedgehog Signaling MutationsSignal Transduction In Hedgehog PathwaySmall Cell Lung Cancer Association
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Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome
Heidi Hahn, Carol Wicking, Peter G. Zaphiropoulos et al. · Cell · 1996 · 2K citations · Full text
Human Homolog of <b> <i>patched</i> </b> , a Candidate Gene for the Basal Cell Nevus Syndrome
Ronald L. Johnson, Alana Rothman, Jingwu Xie et al. · Science · 1996 · 1.9K citations
Life Sciences, Genetics, Oncology +17
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
Sarah P. Thayer, Marina Pasca di Magliano, Patrick W. Heiser et al. · Nature · 2003 · 1.5K citations · Full text
Medicine, Cancer Biology, Oncology +12
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
James Chen, Jussi Taipale, Michael K. Cooper et al. · Genes & Development · 2002 · 1.5K citations · Full text
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
David M. Berman, Sunil Karhadkar, Anirban Maitra et al. · Nature · 2003 · 1.3K citations
Medicine, Cancer Biology, Oncology +14