Nature · 1989 · 247 citations · 10 references
Life SciencesGeneticsImmunologyAdaptive ImmunityImmunoregulationTransplant ImmunologyHistocompatibilityHistocompatibility AntigensImmune ToleranceImmunological ToleranceMajor Histocompatibility ComplexTolerance MechanismsClass I Histocompatibility Antigens
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T cell tolerance by clonal elimination in the thymus
John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
Paweł Kisielow, Horst Blüthmann, Uwe D. Staerz et al. · Nature · 1988 · 1.7K citations
Positive and negative selection of an antigen receptor on T cells in transgenic mice
William C. Sha, Christopher A. Nelson, Rodney D. Newberry et al. · Nature · 1988 · 744 citations
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells
David Lo, Linda C. Burkly, Georg Widera et al. · Cell · 1988 · 339 citations