Cell-Active Dual Specificity Phosphatase Inhibitors Identified by High-Content Screening

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

Molecular Biology, Small Molecule Inhibitor, Cytoskeleton +18

PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL SYSTEMS

Ruth I. Geran, Nathaniel H. Greenberg, Marylea MacDonald et al. · Cancer chemotherapy reports. Part 1 · 1972 · 1.1K citations

Animal Testing, Biologic Agent, Bioassay-guided Isolation +5

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

Anne Brunet · The EMBO Journal · 1999 · 602 citations · Full text

Cell Cycle Entry, Signal Transduction, Developmental Biology +10

CDC25 Phosphatases as Potential Human Oncogenes

Konstantin Galaktionov, Arthur K. Lee, Jens Eckstein et al. · Science · 1995 · 504 citations

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.

Linda Groom, Alan A. Sneddon, Dario R. Alessi et al. · The EMBO Journal · 1996 · 412 citations · Full text

Signal Transduction, Rk/p38 Kinases, Biochemistry +11