Concepedia

Augmentation of Response to Chemotherapy by microRNA-506 Through Regulation of RAD51 in Serous Ovarian Cancers

Guoyan Liu, Da Yang, Rajesha Rupaimoole, Chad V. Pecot, Yan Sun, Lingegowda S. Mangala, Xia Li, Ping Ji, David Cogdell, Limei Hu,

JNCI Journal of the National Cancer Institute · 2015 · 124 citations · 39 references

DOIFull text

Open access

Abstract

MiR-506 is a robust clinical marker for chemotherapy response and survival in serous ovarian cancers and has important therapeutic value in sensitizing cancer cells to chemotherapy.

References

39

Cancer statistics, 2013

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2013 · 11.9K citations · Full text

Adjusting batch effects in microarray expression data using empirical Bayes methods

W. Evan Johnson, Cheng Li, Ariel Rabinovic · Biostatistics · 2006 · 8.7K citations · Full text

Integrated genomic analyses of ovarian carcinoma

Debra Bell, Andrew Berchuck, Wendy Winckler · Nature · 2011 · 8K citations · Full text

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.5K citations

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.1K citations

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