Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

Barbara B. Knowles, Chin C. Howe, David P. Aden · Science · 1980 · 2K citations

Medicine, Cancer Biology, Molecular Biology +12

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

Walter M.A. Westerink, W.G.E.J. Schoonen · Toxicology in Vitro · 2007 · 525 citations

Medicine, Biochemistry, Pharmacology +16

Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B.

Joseph L. Dixon, S Furukawa, Henry N. Ginsberg · Journal of Biological Chemistry · 1991 · 419 citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

Lei Guo, Stacey L. Dial, Leming Shi et al. · Drug Metabolism and Disposition · 2010 · 341 citations · Full text

Medicine, Pharmacology, Toxicology +13

Characterization of the major apolipoproteins secreted by two human hepatoma cell lines

Vassilis I. Zannis, Jan L. Breslow, Thomas R. Sangiacomo et al. · Biochemistry · 1981 · 260 citations

Life Sciences, Biochemistry, Molecular Biology +11