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Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

Lei Guo, Stacey L. Dial, Leming Shi, William S. Branham, Jie Liu, Jia‐Long Fang, Bridgett Green, Helen Deng, Jim Kaput, Baitang Ning

Drug Metabolism and Disposition · 2010 · 341 citations · 25 references

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25

Mapping the Genetic Architecture of Gene Expression in Human Liver

Eric E. Schadt, Cliona Molony, Eugene Chudin et al. · PLoS Biology · 2008 · 928 citations · Full text

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Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

Yukio Ando, Hideo Saka, Maki Ando et al. · PubMed · 2000 · 788 citations

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COMPARISON OF PRIMARY HUMAN HEPATOCYTES AND HEPATOMA CELL LINE HEPG2 WITH REGARD TO THEIR BIOTRANSFORMATION PROPERTIES

Stefan Wilkening, Frank Stahl, Augustinus Bader · Drug Metabolism and Disposition · 2003 · 771 citations

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EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS

Caroline Aninat, Amélie Piton, Denise Glaise et al. · Drug Metabolism and Disposition · 2005 · 678 citations

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Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

Walter M.A. Westerink, W.G.E.J. Schoonen · Toxicology in Vitro · 2007 · 525 citations

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