Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor.

SH2 domains recognize specific phosphopeptide sequences

Cell · 1993 · 2.7K citations

Protein Function, Signal Transduction, Medicine +7

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

László Buday, Julian Downward · Cell · 1993 · 1.1K citations

Exchange Factor, Epidermal Growth Factor, Signal Transduction +8

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

Huntington Potter, L Weir, Philip Leder · Proceedings of the National Academy of Sciences · 1984 · 883 citations · Full text

Lymphocyte Development, Genetics, Immunology +22

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

Bryan Irving, Arthur Weiss · Cell · 1991 · 792 citations

Signal Transduction, Cell Signaling, T-regulatory Cell +8

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos

Jean Paul Olivier · Cell · 1993 · 547 citations

Molecular Physiology, Signal Transduction, Signaling Pathway +11