Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

A. Phillip West, Igor E. Brodsky, Christoph Rahner et al. · Nature · 2011 · 1.6K citations · Full text

Life Sciences, Immunology, Microbiology +13

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

Denis Arsenijevic, Hiroki Onuma, Claire Pecqueur et al. · Nature Genetics · 2000 · 1.1K citations

Life Sciences, Genetics, Immunology +16

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

Dawang Zhou, Claudius Conrad, Fan Xia et al. · Cancer Cell · 2009 · 936 citations · Full text

Medicine, Genetics, Oncology +13

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

Ariel C. Bulua, Anna Simon, Ravikanth Maddipati et al. · The Journal of Experimental Medicine · 2011 · 846 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

A Conserved MST-FOXO Signaling Pathway Mediates Oxidative-Stress Responses and Extends Life Span

Maria K. Lehtinen, Zengqiang Yuan, Peter R. Boag et al. · Cell · 2006 · 834 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12