Concepedia

Publication | Closed Access

Zoledronic acid-induced cytotoxicity through endoplasmic reticulum stress triggered REDD1-mTOR pathway in breast cancer cells.

26

Citations

27

References

2013

Year

Ya-Chun Lan, Chia-Ling Chang, Ming-Ta Sung, Pen-Hui Yin, Chia‐Chi Hsu, Kuo-Chung Wang, Hsin‐Chen Lee, Ling‐Ming Tseng, Chin‐Wen Chi
PubMed

Abstract

Taken together, these results indicated that ZOL-induced cell death was caused by endoplasmic reticulum stress activating PERK-eIF2α-CHOP pathway to induce REDD1 expression and inhibit the mTOR pathway.

References

YearCitations

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