Journal of Alzheimer s Disease · 2006 · 470 citations · 7 references
MedicineNeurologyNeuroscienceDementiaNeurobiology Of DiseaseNeurodegenerationAlzheimer DiseaseDementia SyndromesNeurodegenerative DiseasesNeurodegenerative DisordersNeuropathology Of AgingNeuropathology Of DementiaAlzheimer Disease DementiaAlzheimer Disease ProgressionAlzheimer Disease Tau PathologyAmyloid Beta AggregationAmyloid Beta PlaquesAmyloid FibrilsAmyloid PlaquesNeurodegenerative Cascade
Here I recap the scientific and personal background of the delineation of the amyloid cascade hypothesis for Alzheimer's disease that I wrote with Gerry Higgins and the events leading to the writing of that influential review.
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Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type
Efrat Levy, M. D. Carman, Ivan Fernandez‐Madrid et al. · Science · 1990 · 1.4K citations
The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21
Peter St George‐Hyslop, Rudolph E. Tanzi, Ronald J. Polinsky et al. · Science · 1987 · 1.2K citations
Michel Goedert, Claude M. Wischik, R. Anthony Crowther et al. · Proceedings of the National Academy of Sciences · 1988 · 1.1K citations · Full text