Paired helical filament tau in Alzheimer's disease. The kinase connection.

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

Life Sciences, Neurology, Neuroscience +17

A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau

Virginia M.‐Y. Lee, Brian J. Balin, László Ötvös et al. · Science · 1991 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +17

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

David Drechsel, Anthony A. Hyman, Melanie H. Cobb et al. · Molecular Biology of the Cell · 1992 · 973 citations

Life Sciences, Cell Biology, Molecular Biology +17

Abnormal tau phosphorylation at Ser396 in alzheimer's disease recapitulates development and contributes to reduced microtubule binding

Gregory T. Bramblett, Michel Goedert, Ross Jakes et al. · Neuron · 1993 · 898 citations

Life Sciences, Neurobiology, Neuroscience +12

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase

Diane P. Hanger, Kenneth Hughes, James R. Woodgett et al. · Neuroscience Letters · 1992 · 729 citations

Life Sciences, Molecular Biology, Neuroscience +17