A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Martin Scheffner, Jon M. Huibregtse, Richard D. Vierstra et al. · Cell · 1993 · 2.4K citations

Hpv-16 E6, Ubiquitin-protein Ligase, Protein Function +4

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

Gabriel Fenteany, Robert F. Standaert, William S. Lane et al. · Science · 1995 · 1.6K citations

Lactacystin Analogs, Lmp7 Proteasome Subunit, Protein Function +12

Degradation of CFTR by the ubiquitin-proteasome pathway

Cristina L. Ward, Satoshi ŌMURA, Ron R. Kopito · Cell · 1995 · 1.3K citations · Full text

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

Mathias Treier, Lena Staszewski, Dirk Bohmann · Cell · 1994 · 927 citations

Signal Transduction, Cell Regulation, Molecular Regulation +10

Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

Giorgio Lagna, Akiko Hata, Ali Hemmati‐Brivanlou et al. · Nature · 1996 · 911 citations

Molecular Physiology, Signal Transduction, Signaling Pathway +8