Concepedia

Imiquimod-induced psoriasis-like skin inflammation is suppressed by BET bromodomain inhibitor in mice through RORC/IL-17A pathway modulation

Ahmed Nadeem, Naif O. Al‐Harbi, Mohamed M. Al-Harbi, Ahmed M. El‐Sherbeeny, Sheikh F. Ahmad, Nahid Siddiqui, Mushtaq Ahmad Ansari, Khairy M. A. Zoheir, Sabry M. Attia, Khaled Alhosaini,

Pharmacological Research · 2015 · 120 citations · 24 references

DOI

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References

24

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

, , +16

Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

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Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

Peter P. Bradley, Dennis A. Priebat, Robert D. Christensen et al. · Journal of Investigative Dermatology · 1982 · 3.6K citations · Full text

, , +16

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

Jake Delmore, Ghayas C. Issa, Madeleine E. Lemieux et al. · Cell · 2011 · 2.8K citations · Full text

, , +10