Concepedia

T cell receptor dwell times control the kinase activity of Zap70

Christian Klammt, Lucie Novotná, Dongyang Li, Miriam Wolf, Amy L. Blount, Kai Zhang, Jonathan R. Fitchett, Björn F. Lillemeier

Nature Immunology · 2015 · 81 citations · 32 references

DOI

Concepts

References

32

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

André Veillette, Michael A. Bookman, Eva Horak et al. · Cell · 1988 · 1.4K citations

, , +14

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

Andrew C. Chan, Makio Iwashima, Christoph W. Turck et al. · Cell · 1992 · 1K citations

, , +6

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

Stephen C. Bunnell, David I. Hong, Julia R. Kardon et al. · The Journal of Cell Biology · 2002 · 620 citations · Full text

, , +17

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinase

Enrico Arpaia, Michal Shahar, Harjit Dadi et al. · Cell · 1994 · 554 citations

, , +16

Essential role for ZAP-70 in both positive and negative selection of thymocytes

Izumi Negishi, Noboru Motoyama, Kei-ichi Nakayama et al. · Nature · 1995 · 550 citations

, , +11