Izumi Negishi

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

Noboru Motoyama, Fanping Wang, Kevin A. Roth et al. · Science · 1995 · 1.2K citations

Life Sciences, Developmental Biology, Neuroscience +17

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

Noriko Sakaguchi, Takeshi Takahashi, Hiroshi Hata et al. · Nature · 2003 · 875 citations

Life Sciences, Genetics, Immunology +14

Essential role for ZAP-70 in both positive and negative selection of thymocytes

Izumi Negishi, Noboru Motoyama, Kei-ichi Nakayama et al. · Nature · 1995 · 550 citations

Life Sciences, Cell Biology, Immunology +11

Disappearance of the Lymphoid System in Bcl-2 Homozygous Mutant Chimeric Mice

Kei-ichi Nakayama, Keiko Nakayama, Izumi Negishi et al. · Science · 1993 · 401 citations

Life Sciences, Cell Biology, Immunology +15

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia.

Keiko Nakayama, Keiko Nakayama, Izumi Negishi et al. · Proceedings of the National Academy of Sciences · 1994 · 395 citations

Life Sciences, Genetics, Molecular Biology +14