Izumi Negishi

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

Noboru Motoyama, Fanping Wang, Kevin A. Roth et al. · Science · 1995 · 1.2K citations

Lymphocyte Development, Bcl-x-deficient Mice, Apoptosis +18

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

Noriko Sakaguchi, Takeshi Takahashi, Hiroshi Hata et al. · Nature · 2003 · 858 citations

Rheumatology, Immunogenetics, Zap-70 Gene Causes +7

Essential role for ZAP-70 in both positive and negative selection of thymocytes

Izumi Negishi, Noboru Motoyama, Kei-ichi Nakayama et al. · Nature · 1995 · 548 citations

Signal Transduction, Essential Role, Lymphocyte Development +8

Disappearance of the Lymphoid System in Bcl-2 Homozygous Mutant Chimeric Mice

Kei-ichi Nakayama, Keiko Nakayama, Izumi Negishi et al. · Science · 1993 · 400 citations

Knockout Mouse, Lymphoid Neoplasia, Immunogenetics +14

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia.

Keiko Nakayama, Keiko Nakayama, Izumi Negishi et al. · Proceedings of the National Academy of Sciences · 1994 · 395 citations · Full text

Bcl-2 Beta Transcripts, Lymphocyte Development, Immunology +17