Bioprojet (France)

Highly potent and selective ligands for histamine H3-receptors

J.M. Arrang, M. Garbarg, J.-C. Lancelo et al. · Nature · 1987 · 900 citations

Biochemistry, Functional Selectivity, Medicine +5

Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

Maria Pilla, Sylvie Perachon, François Sautel et al. · Nature · 1999 · 568 citations

Selective Inhibition, Substance Abuse, Behavioral Sciences +11

High constitutive activity of native H3 receptors regulates histamine neurons in brain

Séverine Morisset‐Lopez, A. Rouleau, Xavier Ligneau et al. · Nature · 2000 · 462 citations

Histamine Neurons, Neurophysiology, Synaptic Transmission +12

Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse

Lionel C. Clément, Hélène Poirier, Isabelle Niot et al. · Journal of Lipid Research · 2002 · 357 citations · Full text

Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial

Yves Dauvilliers, Claudio L. Bassetti, Gert Jan Lammers et al. · The Lancet Neurology · 2013 · 346 citations

Pitolisant Versus Placebo, Psychoactive Drug, Psychiatry +7