A. Rouleau

High constitutive activity of native H3 receptors regulates histamine neurons in brain

Séverine Morisset‐Lopez, A. Rouleau, Xavier Ligneau et al. · Nature · 2000 · 463 citations

Life Sciences, Neuroscience, Pharmacology +11

BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, Hydrochloride], a Nonimidazole Inverse Agonist/Antagonist at the Human Histamine H3 Receptor: Preclinical Pharmacology

Xavier Ligneau, David Perrin, Laurent Landais et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 234 citations

Medicine, Neuroscience, Pharmacology +10

S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist.

M. Garbarg, J.M. Arrang, A. Rouleau et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 157 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Protean agonism at histamine H ₃ receptors <i>in vitro</i> and <i>in vivo</i>

Florence Gbahou, A. Rouleau, Séverine Morisset‐Lopez et al. · Proceedings of the National Academy of Sciences · 2003 · 142 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Histamine H₃‐receptor‐mediated [³⁵S]GTPγ[S] binding: evidence for constitutive activity of the recombinant and native rat and human H₃ receptors

A. Rouleau, Xavier Ligneau, J Tardivel‐Lacombe et al. · British Journal of Pharmacology · 2002 · 125 citations · Full text

Medicine, Pharmacology, Cell Signaling +11