Xavier Ligneau

High constitutive activity of native H3 receptors regulates histamine neurons in brain

Séverine Morisset‐Lopez, A. Rouleau, Xavier Ligneau et al. · Nature · 2000 · 462 citations

Histamine Neurons, Neurophysiology, Synaptic Transmission +12

A detailed mapping of the histamine H3 receptor and its gene transcripts in rat brain

Catherine Pillot, Anne Héron, Véronique Cochois et al. · Neuroscience · 2002 · 339 citations

Histamine H3 Receptor, Molecular Physiology, Neurotransmitter +11

An inverse agonist of the histamine H3 receptor improves wakefulness in narcolepsy: Studies in orexin−/− mice and patients

Jian‐Sheng Lin, Yves Dauvilliers, Isabelle Arnulf et al. · Neurobiology of Disease · 2007 · 263 citations · Full text

Histamine H3 Receptor, Sleep Disorders, Sleep +13

Neurochemical and Behavioral Effects of Ciproxifan, A Potent Histamine H3-Receptor Antagonist

Xavier Ligneau, Jian‐Sheng Lin, Giovanna Vanni-Mercier et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 240 citations

BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, Hydrochloride], a Nonimidazole Inverse Agonist/Antagonist at the Human Histamine H3 Receptor: Preclinical Pharmacology

Xavier Ligneau, David Perrin, Laurent Landais et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 233 citations