Concepedia

Zinc Finger Array Assembly

Zinc Finger Array Assembly is a molecular engineering method that involves the systematic design and concatenation of individual zinc finger protein domains into a polypeptide array engineered to recognize and bind specific DNA sequences with high affinity and selectivity.

16

Publications

1.1K

Citations

72

Authors

25

Institutions

Publications per year

2017–2026

1

Parents

Publications

16

Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code 1 1Edited by P. E. Wright

Scot A. Wolfe, Harvey A. Greisman, Elizabeth Ramm et al. · Journal of Molecular Biology · 1999 · 183 citations

, , +9

Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA

Mark P. Foster, Deborah S. Wuttke, Ishwar Radhakrishnan et al. · Nature Structural Biology · 1997 · 127 citations

, , +15

An optimized two-finger archive for ZFN-mediated gene targeting

Ankit Gupta, Ryan Christensen, Amy L. Rayla et al. · Nature Methods · 2012 · 121 citations

, , +9

Highly active zinc-finger nucleases by extended modular assembly

Mital S. Bhakta, Isabelle Henry, David G. Ousterout et al. · Genome Research · 2012 · 99 citations · Full text

, , +13

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

Pablo Pérez‐Piñera, David G. Ousterout, Matthew T. Brown et al. · Nucleic Acids Research · 2011 · 95 citations · Full text

, , +13

1–5 of 16

Authors

72

  1. SA
    Scot A. Wolfe

    University of Massachusetts Chan Medical School, United States

    4 publications · 400 citations

    4

    h-index

  2. ER
    Elizabeth Ramm

    Massachusetts Institute of Technology, United States

    2 publications · 250 citations

    2

    h-index

  3. GD
    Gary D. Stormo

    Washington University in St. Louis, United States

    2 publications · 150 citations

    2

    h-index

  4. AL
    Abirami Lakshmanan

    University of Massachusetts Chan Medical School, United States

    2 publications · 150 citations

    2

    h-index

  5. CA
    Charles A. Gersbach

    Duke University, United States

    2 publications · 194 citations

    2

    h-index

1–5 of 72

Institutions

25

  1. Washington University in St. Louis

    St Louis, United States

    2 h-index

    11 publications

    503 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    7 publications

    933 citations

  3. University of Massachusetts Chan Medical School

    Worcester, United States

    2 h-index

    5 publications

    513 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    7 publications

    933 citations

  5. Duke University

    Durham, United States

    2 h-index

    6 publications

    578 citations

  6. Scripps Research Institute

    San Diego, United States

    2 h-index

    12 publications

    1.3K citations

  7. Kyoto University

    Kyoto, Japan

    1 h-index

    1 publications

    37 citations

  8. Makerere University

    Kampala, Uganda

    1 h-index

    1 publications

    21 citations

1–8 of 25

Venues

  1. Nucleic Acids Research

    4 publications · 236 citations

    4

    h-index

  2. Journal of Industrial Microbiology & Biotechnology

    JIM&B · 1 publications · 29 citations

    1

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 1 publications · 37 citations

    1

    h-index

  4. Nature Structural Biology

    1 publications · 127 citations

    1

    h-index

  5. Nature Protocols

    1 publications · 91 citations

    1

    h-index

1–5