Concepedia

Whole-cell Screening

Whole-Cell Screening is a biocatalyst screening method that employs intact microbial or eukaryotic cells as catalytic entities to evaluate enzyme activity or metabolic function directly within the cellular environment, distinguishing it from cell-free or purified enzyme assays.

141

Publications

8K

Citations

1.1K

Authors

308

Institutions

Publications per year

2017–2026

53

Parents

Publications

141

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

Kévin Pethe, Patrícia Carvalho de Sequeira, Sanjay Agarwalla et al. · Nature Communications · 2010 · 308 citations · Full text

, , +12

High content screening applied to large-scale cell biology

Vinod Joseph Abraham · Trends in biotechnology · 2003 · 289 citations

, , +10

Campylobacter cinaedi (sp. nov.) and Campylobacter fennelliae (sp, nov.): Two New Campylobacter Species Associated with Enteric Disease in Homosexual Men

P A Totten, C. L. Fennell, Fred C. Tenover et al. · The Journal of Infectious Diseases · 1985 · 278 citations

, , +15

Whole cell- and protein-based biosensors for the detection of bioavailable heavy metals in environmental samples

Philippe Corbisier, Daniël van der Lelie, Brigitte Borremans et al. · Analytica Chimica Acta · 1999 · 265 citations

, , +17

Identification of Novel Inhibitors of <i>M. tuberculosis</i> Growth Using Whole Cell Based High-Throughput Screening

Sarah A. Stanley, Sarah Schmidt Grant, Tomohiko Kawate et al. · ACS Chemical Biology · 2012 · 253 citations

, , +13

1–5 of 141

Authors

1.1K

  1. AT
    Aloysius T. Nchinda

    University of Cape Town, South Africa

    6 publications · 342 citations

    6

    h-index

  2. SW
    Sergio Wittlin

    Swiss Tropical and Public Health Institute, Switzerland

    6 publications · 368 citations

    6

    h-index

  3. KC
    Kelly Chibale

    University of Cape Town, South Africa

    6 publications · 342 citations

    6

    h-index

  4. VM
    Vicky M. Avery

    Griffith University, Australia

    5 publications · 335 citations

    5

    h-index

  5. LB
    Lluís Ballell

    GlaxoSmithKline (Spain), Spain

    5 publications · 405 citations

    5

    h-index

1–5 of 1.1K

Institutions

308

  1. University of Cape Town

    Rondebosch, South Africa

    9 h-index

    68 publications

    3.5K citations

  2. Medicines for Malaria Venture

    Geneva, Switzerland

    7 h-index

    21 publications

    1.2K citations

  3. GlaxoSmithKline (Spain)

    Madrid, Spain

    7 h-index

    58 publications

    4.2K citations

  4. Griffith University

    Brisbane, Australia

    6 h-index

    13 publications

    751 citations

  5. University of Basel

    Basel, Switzerland

    6 h-index

    6 publications

    368 citations

  6. Swiss Tropical and Public Health Institute

    Allschwil, Switzerland

    6 h-index

    6 publications

    368 citations

  7. University of Birmingham

    Birmingham, United Kingdom

    5 h-index

    22 publications

    2.8K citations

  8. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    5 h-index

    72 publications

    10.6K citations

1–8 of 308

Venues

  1. Journal of Medicinal Chemistry

    12 publications · 744 citations

    12

    h-index

  2. Antimicrobial Agents and Chemotherapy

    AAC · 10 publications · 735 citations

    10

    h-index

  3. Scientific Reports

    9 publications · 337 citations

    9

    h-index

  4. PLoS ONE

    8 publications · 712 citations

    8

    h-index

  5. Molecules

    4 publications · 71 citations

    4

    h-index

1–5