Tomohiko Kawate

Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

Huw M. Nash, Steven D. Bruner, Orlando D. Schärer et al. · Current Biology · 1996 · 436 citations · Full text

Genome Instability, Cellular Enzymology, Biochemistry +6

Identification of Novel Inhibitors of <i>M. tuberculosis</i> Growth Using Whole Cell Based High-Throughput Screening

Sarah A. Stanley, Sarah Schmidt Grant, Tomohiko Kawate et al. · ACS Chemical Biology · 2012 · 252 citations

Drug Target, Tuberculosis Prevention, Immunology +20

Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes

Eachan O. Johnson, Emily LaVerriere, Emma Office et al. · Nature · 2019 · 173 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Pulmonary Tuberculosis +9

Diarylcoumarins inhibit mycolic acid biosynthesis and kill <i>Mycobacterium tuberculosis</i> by targeting FadD32

Sarah A. Stanley, Tomohiko Kawate, Noriaki Iwase et al. · Proceedings of the National Academy of Sciences · 2013 · 95 citations · Full text

Immunology, Cell Death, Mycolic Acid Biosynthesis +18

Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model

Sarah Schmidt Grant, Tomohiko Kawate, Partha P. Nag et al. · ACS Chemical Biology · 2013 · 86 citations · Full text

Bioorganic Chemistry, Mycobacterium Tuberculosis Infection, Antimicrobial Chemotherapy +22