Noriaki Iwase

Identification of Novel Inhibitors of <i>M. tuberculosis</i> Growth Using Whole Cell Based High-Throughput Screening

Sarah A. Stanley, Sarah Schmidt Grant, Tomohiko Kawate et al. · ACS Chemical Biology · 2012 · 252 citations

Drug Target, Tuberculosis Prevention, Immunology +20

Diarylcoumarins inhibit mycolic acid biosynthesis and kill <i>Mycobacterium tuberculosis</i> by targeting FadD32

Sarah A. Stanley, Tomohiko Kawate, Noriaki Iwase et al. · Proceedings of the National Academy of Sciences · 2013 · 95 citations · Full text

Immunology, Cell Death, Mycolic Acid Biosynthesis +18

Synthesis and structure–activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32

Tomohiko Kawate, Noriaki Iwase, Motohisa Shimizu et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 59 citations

Combinatorial Chemistry, Phenyl-substituted Coumarins, Derivatives +7

Baeyer-Villiger Monooxygenases EthA and MymA Are Required for Activation of Replicating and Non-replicating Mycobacterium tuberculosis Inhibitors

Sarah Schmidt Grant, Samantha Wellington, Tomohiko Kawate et al. · Cell chemical biology · 2016 · 58 citations · Full text

Myma Are Required, Medical Microbiology, Pulmonary Tuberculosis +11

Substrate Specificity of 2-Deoxy-<i>scyllo</i>-inosose Synthase, the Starter Enzyme for 2-Deoxystreptamine Biosynthesis, toward Deoxyglucose-6-phosphates and Proposed Mechanism

Noriaki Iwase, Fumitaka Kudo, Noriaki Yamauchi · Bioscience Biotechnology and Biochemistry · 1998 · 21 citations · Full text

Bioorganic Chemistry, Aldo-keto Reductase, 2-Deoxy-scyllo-inosose Synthase +16