Concepedia

Vector-mediated Immune Suppression

Vector-Mediated Immune Suppression is a biological phenomenon in which hematophagous arthropod vectors, through the secretion of pharmacologically active molecules in their saliva during host feeding, actively modulate or inhibit host immune responses to facilitate pathogen transmission and establishment.

7

Publications

442

Citations

52

Authors

18

Institutions

Publications per year

2017–2026

1

Parents

Publications

7

Encapsulation of recombinant adenovirus into alginate microspheres circumvents vector-specific immune response

G. S. Sailaja, Harm HogenEsch, Adam North et al. · Gene Therapy · 2002 · 111 citations · Full text

, , +12

Immunological control of hematophagous arthropod vectors: Utilization of novel antigens

Stephen K. Wikel · Veterinary Parasitology · 1988 · 86 citations

, , +16

Exponential Enhancement of Oncolytic Vesicular Stomatitis Virus Potency by Vector-mediated Suppression of Inflammatory Responses In Vivo

Jennifer Altomonte, Lan Wu, Li Chen et al. · Molecular Therapy · 2007 · 80 citations · Full text

, , +17

Readministration of Adenovirus Vector in Nonhuman Primate Lungs by Blockade of CD40-CD40 Ligand Interactions

Narendra Chirmule, Steven E. Raper, Linda C. Burkly et al. · Journal of Virology · 2000 · 59 citations

, , +15

Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment

Guy Caljon, J. Sternberg, Marc Coosemans et al. · International Journal for Parasitology · 2006 · 52 citations

, , +13

1–5 of 7

Authors

52

  1. JM
    James M. Wilson

    University of Pennsylvania, United States

    1 publications · 59 citations

    1

    h-index

  2. CD
    Chuantian Ding

    National Institutes of Health, United States

    1 publications · 36 citations

    1

    h-index

  3. GC
    Guy Caljon

    University of Antwerp, Belgium

    1 publications · 52 citations

    1

    h-index

  4. JA
    Jennifer Altomonte

    Technical University of Munich, Germany

    1 publications · 80 citations

    1

    h-index

  5. RT
    Raffaella Toso

    Children's Hospital of Philadelphia, United States

    1 publications · 18 citations

    1

    h-index

1–5 of 52

Institutions

18

  1. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    6 publications

    313 citations

  2. University of North Dakota

    Grand Forks, United States

    1 h-index

    1 publications

    86 citations

  3. United States Military Academy

    West Point, United States

    1 h-index

    1 publications

    111 citations

  4. Vlaams Instituut voor Biotechnologie

    Ghent, Belgium

    1 h-index

    1 publications

    52 citations

  5. Children's Hospital of Philadelphia

    Philadelphia, United States

    1 h-index

    4 publications

    72 citations

  6. Center for Biologics Evaluation and Research

    Silver Spring, United States

    1 h-index

    3 publications

    108 citations

  7. United States Food and Drug Administration

    Silver Spring, United States

    1 h-index

    3 publications

    108 citations

  8. National Heart Lung and Blood Institute

    Bethesda, United States

    1 h-index

    2 publications

    72 citations

1–8 of 18

Venues

  1. Gene Therapy

    1 publications · 111 citations

    1

    h-index

  2. 1

    h-index

  3. Human Gene Therapy

    1 publications · 36 citations

    1

    h-index

  4. Molecular Therapy

    1 publications · 80 citations

    1

    h-index

  5. Journal of Virology

    JVI · 1 publications · 59 citations

    1

    h-index

1–5