Encapsulation of recombinant adenovirus into alginate microspheres circumvents vector-specific immune response

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.

Yang Yang, Frederick A. Nunes, Klára Berencsi et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations · Full text

Immunology, Recombinant Adenoviruses, Immunotherapy +19

Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

Ya‐Wen Yang, Qunyang Li, Hildegund C.J. Ertl et al. · Journal of Virology · 1995 · 1K citations · Full text

Viral Pathogenesis, Immunology, Recombinant Adenoviruses +17

Immune responses to adenovirus and adeno-associated virus in humans

Narendra Chirmule, Kathleen J. Propert, Susan Magosin et al. · Gene Therapy · 1999 · 677 citations

Adeno-associated Virus, Viral Pathogenesis, Immunology +4

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression.

Yue Dai, Edward M. Schwarz, Danling Gu et al. · Proceedings of the National Academy of Sciences · 1995 · 594 citations

Targeted gene delivery by tropism-modified adenoviral vectors

Joanne T. Douglas, Buck E. Rogers, Maryland E. Rosenfeld et al. · Nature Biotechnology · 1996 · 430 citations

Virology, Gene Delivery, Gene Vector +2