Raffaella Toso

Removal of B-domain Sequences from Factor V Rather than Specific Proteolysis Underlies the Mechanism by Which Cofactor Function Is Realized

Raffaella Toso, Rodney M. Camire · Journal of Biological Chemistry · 2004 · 88 citations · Full text

Zymogen-like factor Xa variants restore thrombin generation and effectively bypass the intrinsic pathway in vitro

Matthew W. Bunce, Raffaella Toso, Rodney M. Camire · Blood · 2010 · 76 citations

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia

Lacramioara Ivanciu, Raffaella Toso, Paris Margaritis et al. · Nature Biotechnology · 2011 · 71 citations

Hematology, Immunology, Pathology +5

Factor V Leiden improves in vivo hemostasis in murine hemophilia models

Alexander Schlachterman, Joerg Schuettrumpf, J.H. LIU et al. · Journal of Thrombosis and Haemostasis · 2005 · 66 citations

Inflammation, Thrombosis, Thrombopoiesis +11

Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

Denise E. Sabatino, Christian Furlan Freguia, Raffaella Toso et al. · Blood · 2009 · 60 citations · Full text