Concepedia

Transduction Efficiency Assessment

Transduction Efficiency Assessment is a methodological metric used in gene therapy research that quantifies the proportion of target cells successfully expressing a transgene following vector-mediated delivery, distinguishing it from broader efficacy measures by specifically evaluating the functional outcome of transduction processes.

604

Publications

32.2K

Citations

3.8K

Authors

936

Institutions

Publications per year

2017–2026

126

Parents

Publications

604

Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

Zhong Li, Baozheng Li, Cathryn Mah et al. · Proceedings of the National Academy of Sciences · 2008 · 549 citations · Full text

, , +17

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

Dominik F. Aschauer, Sebastian Kreuz, Simon Rumpel · PLoS ONE · 2013 · 523 citations · Full text

, , +17

Effect of Alpha Interferon on the Hepatitis C Virus Replicon

Ju‐Tao Guo, V. Bichko, Christoph Seeger · Journal of Virology · 2001 · 442 citations

, , +17

Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

A. Dusty Miller, Ming-Fan Law, Inder M. Verma · Molecular and Cellular Biology · 1985 · 332 citations · Full text

, , +14

The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants.

Johnny Huard, Hanns Lochmüller, Gyula Acsádi et al. · PubMed · 1995 · 332 citations

, , +8

1–5 of 604

Authors

3.8K

  1. AS
    Arun Srivastava

    University of Florida, United States

    20 publications · 1.5K citations

    18

    h-index

  2. JM
    James M. Wilson

    University of Pennsylvania, United States

    16 publications · 1.6K citations

    16

    h-index

  3. CL
    Chen Ling

    University of Florida, United States

    13 publications · 703 citations

    12

    h-index

  4. AD
    A. Dusty Miller

    Fred Hutch Cancer Center, United States

    10 publications · 1.3K citations

    10

    h-index

  5. GR
    Giridhara R. Jayandharan

    Christian Medical College, Vellore, India

    9 publications · 569 citations

    9

    h-index

1–5 of 3.8K

Institutions

936

  1. University of Florida

    Gainesville, United States

    28 h-index

    230 publications

    12.8K citations

  2. University of Pennsylvania

    Philadelphia, United States

    21 h-index

    126 publications

    11K citations

  3. Florida College

    Temple Terrace, United States

    20 h-index

    155 publications

    9K citations

  4. Harvard University

    Cambridge, United States

    15 h-index

    63 publications

    4.1K citations

  5. Inserm

    Paris, France

    15 h-index

    82 publications

    3.6K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    50 publications

    2.8K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    14 h-index

    54 publications

    2.9K citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    14 h-index

    63 publications

    5.6K citations

1–8 of 936

Venues

  1. Human Gene Therapy

    106 publications · 6.5K citations

    47

    h-index

  2. Journal of Virology

    JVI · 36 publications · 3.4K citations

    30

    h-index

  3. Molecular Therapy

    33 publications · 2.4K citations

    24

    h-index

  4. The Journal of Gene Medicine

    40 publications · 1.4K citations

    20

    h-index

  5. 20

    h-index

1–5