Concepedia

Trans-regulatory Effects

Trans-Regulatory Effects is a type of gene expression regulatory mechanism in which a transcription factor or regulatory element encoded by one allele influences the expression of a target gene located on a different chromosome or on the homologous chromosome, thereby acting in trans to modulate allele-specific expression.

261

Publications

18.8K

Citations

1.6K

Authors

596

Institutions

Publications per year

2017–2026

87

Parents

Publications

261

Mapping cis- and trans-regulatory effects across multiple tissues in twins

Elin Grundberg, Kerrin S. Small, Åsa K. Hedman et al. · Nature Genetics · 2012 · 787 citations · Full text

, , +11

Trans Effects on Gene Expression Can Drive Omnigenic Inheritance

Xuanyao Liu, Yang Li, Jonathan K. Pritchard · Cell · 2019 · 606 citations · Full text

, , +17

The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer

Xiaying Zheng, Mengge Huang, Lei Xing et al. · Molecular Cancer · 2020 · 522 citations · Full text

, , +14

Contribution of trans regulatory eQTL to cryptic genetic variation in C. elegans

Basten L. Snoek, Mark G. Sterken, R. Bevers et al. · BMC Genomics · 2017 · 445 citations · Full text

, , +17

Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.

Miriam Siekevitz, Mark B. Feinberg, Nikki J. Holbrook et al. · Proceedings of the National Academy of Sciences · 1987 · 404 citations · Full text

, , +17

1–5 of 261

Authors

1.6K

  1. PJ
    Patricia J. Wittkopp

    University of Michigan, United States

    12 publications · 839 citations

    12

    h-index

  2. BP
    Brian P. H. Metzger

    University of Chicago, United States

    4 publications · 278 citations

    4

    h-index

  3. JD
    Joseph D. Coolon

    University of Michigan, United States

    4 publications · 260 citations

    4

    h-index

  4. DB
    David B. Lowry

    Michigan State University, United States

    3 publications · 142 citations

    3

    h-index

  5. BY
    Bing Yang

    Anhui University of Science and Technology, China

    3 publications · 196 citations

    3

    h-index

1–5 of 1.6K

Institutions

596

  1. Harvard University

    Cambridge, United States

    15 h-index

    49 publications

    5K citations

  2. University of Chicago

    Chicago, United States

    14 h-index

    31 publications

    3K citations

  3. University of Michigan

    Ann Arbor, United States

    13 h-index

    40 publications

    2.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    23 publications

    2.3K citations

  5. Cornell University

    Ithaca, United States

    9 h-index

    27 publications

    2.3K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    20 publications

    4.6K citations

  7. Columbia University

    New York, United States

    7 h-index

    19 publications

    596 citations

  8. Stanford University

    Stanford, United States

    7 h-index

    9 publications

    1.4K citations

1–8 of 596

Venues

  1. Genetics

    19 publications · 1.6K citations

    18

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.5K citations

    15

    h-index

  3. PLoS ONE

    11 publications · 442 citations

    11

    h-index

  4. Molecular Biology and Evolution

    MBE · 10 publications · 573 citations

    10

    h-index

  5. Journal of Biological Chemistry

    JBC · 10 publications · 867 citations

    10

    h-index

1–5