Concepedia

Three-dimensional Invasion Models

Three-Dimensional Invasion Models is a computational and experimental framework in cancer research that simulates tumor cell invasion within a spatially resolved, biologically relevant extracellular matrix, distinguishing itself from two-dimensional approaches by incorporating physiological tissue architecture, cell-matrix interactions, and dynamic microenvironmental cues to more accurately recapitulate in vivo invasion mechanisms.

144

Publications

8.6K

Citations

914

Authors

388

Institutions

Publications per year

2017–2026

69

Variants

3D Invasion Models

Parents

Publications

144

Realistic simulation of the 3-D growth of brain tumors in MR images coupling diffusion with biomechanical deformation

Olivier Clatz, Maxime Sermesant, Pierre‐Yves Bondiau et al. · IEEE Transactions on Medical Imaging · 2005 · 359 citations

, , +17

A Comprehensive Panel of Three-Dimensional Models for Studies of Prostate Cancer Growth, Invasion and Drug Responses

Ville Härmä, Johannes Virtanen, Rami Mäkelä et al. · PLoS ONE · 2010 · 347 citations · Full text

, , +17

3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments

Fanben Meng, Carolyn Meyer, Daeha Joung et al. · Advanced Materials · 2019 · 256 citations

, , +17

Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra‐cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum

Hilary A. Kenny, Thomas Krausz, Seiko Yamada et al. · International Journal of Cancer · 2007 · 245 citations · Full text

, , +17

A Mathematical Model of Glioblastoma Tumor Spheroid Invasion in a Three-Dimensional In Vitro Experiment

Andrew M. Stein, Tim Demuth, David L. Mobley et al. · Biophysical Journal · 2006 · 243 citations · Full text

, , +16

1–5 of 144

Authors

914

  1. AJ
    Andrew J. Ewald

    Johns Hopkins University, United States

    5 publications · 239 citations

    5

    h-index

  2. MR
    Matthew R. Lockett

    University of North Carolina at Chapel Hill, United States

    4 publications · 110 citations

    4

    h-index

  3. UC
    Umber Cheema

    University College London, United Kingdom

    3 publications · 170 citations

    3

    h-index

  4. HM
    Hemant M. Kocher

    Queen Mary University of London, United Kingdom

    2 publications · 46 citations

    2

    h-index

  5. ME
    Mark Emberton

    University College London, United Kingdom

    2 publications · 123 citations

    2

    h-index

1–5 of 914

Institutions

388

  1. Johns Hopkins University

    Baltimore, United States

    8 h-index

    58 publications

    4K citations

  2. Johns Hopkins Medicine

    Baltimore, United States

    7 h-index

    48 publications

    3.1K citations

  3. Dalian Medical University

    Dalian, China

    5 h-index

    35 publications

    1.7K citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    5 h-index

    19 publications

    524 citations

  5. Peking University

    Beijing, China

    4 h-index

    9 publications

    621 citations

  6. Queen Mary University of London

    London, United Kingdom

    4 h-index

    27 publications

    795 citations

  7. Arizona State University

    Tempe, United States

    4 h-index

    13 publications

    602 citations

  8. University of Helsinki

    Helsinki, Finland

    3 h-index

    4 publications

    409 citations

1–8 of 388

Venues

  1. Scientific Reports

    8 publications · 455 citations

    8

    h-index

  2. PLoS ONE

    6 publications · 547 citations

    6

    h-index

  3. Integrative Biology

    5 publications · 409 citations

    5

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 520 citations

    4

    h-index

  5. Oncotarget

    4 publications · 192 citations

    4

    h-index

1–5