Matthew R. Lockett

Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase

Phillip W. Snyder, Jasmin Mecinović, Demetri T. Moustakas et al. · Proceedings of the National Academy of Sciences · 2011 · 351 citations · Full text

Engineering, Water Molecules, Molecular Dynamics +16

Water Networks Contribute to Enthalpy/Entropy Compensation in Protein–Ligand Binding

Benjamin Breiten, Matthew R. Lockett, Woody Sherman et al. · Journal of the American Chemical Society · 2013 · 326 citations

Protein Chemistry, Enthalpy/entropy Compensation, Engineering +12

Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues

Paul R. Graves, Lucas J. Aponte‐Collazo, Emily M.J. Fennell et al. · ACS Chemical Biology · 2019 · 195 citations

A paper-based invasion assay: Assessing chemotaxis of cancer cells in gradients of oxygen

Bobak Mosadegh, Matthew R. Lockett, Kyaw Thu Minn et al. · Biomaterials · 2015 · 142 citations · Full text

Health Sciences, Tumor Heterogeneity, Medicine +14

Is it the shape of the cavity, or the shape of the water in the cavity?

Phillip W. Snyder, Matthew R. Lockett, Demetri T. Moustakas et al. · The European Physical Journal Special Topics · 2013 · 140 citations

Anatomy