Is it the shape of the cavity, or the shape of the water in the cavity?

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W. Kauzmann · Advances in protein chemistry · 1959 · 4.9K citations

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Free Volume and Entropy in Condensed Systems III. Entropy in Binary Liquid Mixtures; Partial Molal Entropy in Dilute Solutions; Structure and Thermodynamics in Aqueous Electrolytes

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A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

P. J. Goodford · Journal of Medicinal Chemistry · 1985 · 2.6K citations

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Hydrophobicity at Small and Large Length Scales

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