Concepedia

Thioesterase Domains

Thioesterase Domain is a catalytic domain in polyketide synthase enzymes that belongs to the class of hydrolase domains and is distinguished by its specific function in cleaving thioester bonds to release polyketide chain intermediates or final products during polyketide biosynthesis.

255

Publications

16.5K

Citations

1.1K

Authors

332

Institutions

Publications per year

2017–2026

46

Parents

Publications

255

Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity

Steven J. Kridel, Fumiko Axelrod, Natasha Rozenkrantz et al. · Cancer Research · 2004 · 601 citations · Full text

, , +16

The Crystal Structure of a Mammalian Fatty Acid Synthase

Timm Maier, Marc Leibundgut, Nenad Ban · Science · 2008 · 510 citations

, , +17

Microcystin Biosynthesis in <i>Planktothrix</i> : Genes, Evolution, and Manipulation

Guntram Christiansen, Jutta Fastner, Marcel Erhard et al. · Journal of Bacteriology · 2003 · 372 citations · Full text

, , +11

Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras.

Laura A. Camp, Sandra L. Hofmann · Journal of Biological Chemistry · 1993 · 361 citations · Full text

, , +15

SyrB2 in syringomycin E biosynthesis is a nonheme Fe <sup>II</sup> α-ketoglutarate- and O <sub>2</sub> -dependent halogenase

Frédéric H. Vaillancourt, Jun Yin, Christopher T. Walsh · Proceedings of the National Academy of Sciences · 2005 · 334 citations · Full text

, , +15

1–5 of 255

Authors

1.1K

  1. CT
    Christopher T. Walsh

    Harvard University, United States

    20 publications · 2.5K citations

    19

    h-index

  2. MA
    Mohamed A. Marahiel

    Philipps University of Marburg, Germany

    17 publications · 2.4K citations

    17

    h-index

  3. DE
    David E. Cane

    Brown University, United States

    12 publications · 926 citations

    12

    h-index

  4. CK
    Chaitan Khosla

    Stanford University, United States

    10 publications · 874 citations

    10

    h-index

  5. PF
    Peter F. Leadlay

    University of Cambridge, United Kingdom

    8 publications · 326 citations

    8

    h-index

1–5 of 1.1K

Institutions

332

  1. Harvard University

    Cambridge, United States

    22 h-index

    77 publications

    9.7K citations

  2. Philipps University of Marburg

    Marburg, Germany

    17 h-index

    58 publications

    7.6K citations

  3. Brown University

    Providence, United States

    12 h-index

    49 publications

    4.4K citations

  4. Stanford University

    Stanford, United States

    11 h-index

    51 publications

    4.8K citations

  5. Baylor College of Medicine

    Houston, United States

    8 h-index

    31 publications

    2K citations

  6. Johns Hopkins University

    Baltimore, United States

    7 h-index

    25 publications

    2.6K citations

  7. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    35 publications

    1.5K citations

  8. Shanghai Jiao Tong University

    Shanghai, China

    7 h-index

    40 publications

    1.5K citations

1–8 of 332

Venues

  1. Journal of Biological Chemistry

    JBC · 23 publications · 1.4K citations

    20

    h-index

  2. Biochemistry

    26 publications · 1.5K citations

    20

    h-index

  3. Journal of the American Chemical Society

    JACS · 15 publications · 867 citations

    15

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1.7K citations

    13

    h-index

  5. Chemistry & Biology

    12 publications · 870 citations

    12

    h-index

1–5