Concepedia

Target Gene Mutations

Target Gene Mutations is a molecular epidemiological construct that denotes specific nucleotide alterations in a pathogen's genome at sites known to confer antimicrobial resistance, distinguishing it from other resistance mechanisms by directly implicating defined genetic loci whose modifications reduce drug binding or efficacy.

419

Publications

30.6K

Citations

2.8K

Authors

857

Institutions

Publications per year

2017–2026

159

Parents

Publications

419

A CRISPR/Cas9 toolkit for multiplex genome editing in plants

Hui-Li Xing, Dong Li, Zhi-Ping Wang et al. · BMC Plant Biology · 2014 · 1.7K citations · Full text

, , +16

Integrated genomic and molecular characterization of cervical cancer

Nature · 2017 · 1.6K citations · Full text

, , +17

Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes

Zhen Liang, Kunling Chen, Tingdong Li et al. · Nature Communications · 2017 · 963 citations · Full text

, , +15

The <scp>CRISPR</scp>/<scp>C</scp>as9 system produces specific and homozygous targeted gene editing in rice in one generation

Hui Zhang, Jinshan Zhang, Pengliang Wei et al. · Plant Biotechnology Journal · 2014 · 793 citations · Full text

, , +15

Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry

Alessandro Pastore, Vindi Jurinović, Robert Kridel et al. · The Lancet Oncology · 2015 · 613 citations

, , +17

1–5 of 419

Authors

2.8K

  1. SC
    Sheng Chen

    Hong Kong Polytechnic University, Hong Kong SAR China

    6 publications · 316 citations

    6

    h-index

  2. SS
    Stephan Stilgenbauer

    Universität Ulm, Germany

    5 publications · 675 citations

    5

    h-index

  3. HD
    Hartmut Döhner

    Universität Ulm, Germany

    5 publications · 675 citations

    5

    h-index

  4. ET
    Eugen Tausch

    Universität Ulm, Germany

    4 publications · 637 citations

    4

    h-index

  5. DM
    Daniel Mertens

    German Cancer Research Center, Germany

    4 publications · 651 citations

    4

    h-index

1–5 of 2.8K

Institutions

857

  1. Harvard University

    Cambridge, United States

    10 h-index

    37 publications

    23.8K citations

  2. Inserm

    Paris, France

    10 h-index

    43 publications

    1.8K citations

  3. National Cancer Institute

    Bethesda, United States

    8 h-index

    31 publications

    25.7K citations

  4. Massachusetts General Hospital

    Boston, United States

    7 h-index

    25 publications

    5.7K citations

  5. University of Florida

    Gainesville, United States

    7 h-index

    26 publications

    1.7K citations

  6. Heidelberg University

    Heidelberg, Germany

    7 h-index

    17 publications

    3.4K citations

  7. Johns Hopkins University

    Baltimore, United States

    6 h-index

    17 publications

    1.6K citations

  8. The University of Tokyo

    Tokyo, Japan

    6 h-index

    22 publications

    557 citations

1–8 of 857

Venues

  1. Scientific Reports

    17 publications · 2.3K citations

    16

    h-index

  2. PLoS ONE

    15 publications · 1.1K citations

    14

    h-index

  3. Nucleic Acids Research

    14 publications · 1.3K citations

    13

    h-index

  4. PubMed

    Repository · 15 publications · 731 citations

    12

    h-index

  5. Antimicrobial Agents and Chemotherapy

    AAC · 13 publications · 1.1K citations

    12

    h-index

1–5