Mutations driving CLL and their evolution in progression and relapse

Dan A. Landau, Eugen Tausch, Amaro Taylor‐Weiner, +27

Nature

Genome InstabilitySomatic VariantGenetic DisorderGeneticsGenetic Mechanism +4

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial

Stephan Stilgenbauer, Andrea Schnaiter, Peter Paschka, +28

Blood

Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae.

Ralf Erdmann, Marten Veenhuis, Daniel Mertens, +1

Proceedings of the National Academy of Sciences

BiosynthesisOleic AcidCell DivisionBiochemistryPas Mutants +11

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

Christopher C. Oakes, Marc Seifert, Yassen Assenov, +23

Nature Genetics

Hematological MalignancyChromatinChronic Lymphocytic LeukemiaEpigenetic ChangeGenetics +8

The cdc25B phosphatase is essential for the G 2/M phase transition in human cells

Christiane Lammer, Sybille Wagerer, Rainer Saffrich, +3

Journal of Cell Science

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial

Thorsten Zenz, Sonja Häbe, Tina Denzel, +10

Blood

miR-34a as part of the resistance network in chronic lymphocytic leukemia

Thorsten Zenz, Julia Mohr, Eric Eldering, +9

Blood

Venetoclax resistance and acquired <i>BCL2</i> mutations in chronic lymphocytic leukemia

Eugen Tausch, William Close, Anna Dolnik, +6

Haematologica

Hematological MalignancyLymphoid NeoplasiaHealth SciencesVenetoclax ResistanceImmunology +5

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

Jennifer Edelmann, Karlheinz Holzmann, Florian Miller, +19

Blood

Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB

Angela Garding, Nupur Bhattacharya, Rainer Claus, +24

PLoS Genetics