Concepedia

Tap Transporter Function

TAP Transporter Function is a molecular mechanism in the antigen processing pathway that selectively translocates cytosolic peptides into the endoplasmic reticulum for loading onto Major Histocompatibility Complex class I molecules.

226

Publications

17.1K

Citations

922

Authors

275

Institutions

Publications per year

2017–2026

10

Variants

Transporter Associated With Antigen Processing Function

Parents

Publications

226

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4−8+ T cells

Luc Van Kaer, Philip G. Ashton‐Rickardt, Hidde L. Ploegh et al. · Cell · 1992 · 727 citations

, , +17

Roles for Calreticulin and a Novel Glycoprotein, Tapasin, in the Interaction of MHC Class I Molecules with TAP

Bhanu Sadasivan, Bodo Ortmann, Thomas A. Spies et al. · Immunity · 1996 · 695 citations · Full text

, , +17

Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter

Jacques Neefjes, Frank Momburg, Günter J. Hämmerling · Science · 1993 · 553 citations

, , +17

A Critical Role for Tapasin in the Assembly and Function of Multimeric MHC Class I-TAP Complexes

Bodo Ortmann, James Copeman, Paul J. Lehner et al. · Science · 1997 · 522 citations

, , +16

The major substrates for TAP in vivo are derived from newly synthesized proteins

Eric A. Reits, J. Chris Vos, Monique Grommé et al. · Nature · 2000 · 404 citations

, , +8

1–5 of 226

Authors

922

  1. RT
    Robert Tampé

    Goethe University Frankfurt, Germany

    33 publications · 2.9K citations

    26

    h-index

  2. FM
    Frank Momburg

    German Cancer Research Center, Germany

    18 publications · 2K citations

    16

    h-index

  3. RA
    Rupert Abele

    Goethe University Frankfurt, Germany

    15 publications · 1.1K citations

    15

    h-index

  4. JN
    Jacques Neefjes

    The Netherlands Cancer Institute, Netherlands

    12 publications · 1.9K citations

    12

    h-index

  5. PV
    Peter Van Endert

    Inserm, France

    10 publications · 900 citations

    10

    h-index

1–5 of 922

Institutions

275

  1. Goethe University Frankfurt

    Frankfurt am Main, Germany

    22 h-index

    102 publications

    7.1K citations

  2. Heidelberg University

    Heidelberg, Germany

    20 h-index

    56 publications

    5.9K citations

  3. German Cancer Research Center

    Heidelberg, Germany

    18 h-index

    53 publications

    6K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    16 h-index

    66 publications

    17.7K citations

  5. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    13 h-index

    32 publications

    4.4K citations

  6. Inserm

    Paris, France

    12 h-index

    43 publications

    3.8K citations

  7. University of Cologne

    Cologne, Germany

    10 h-index

    31 publications

    1.3K citations

  8. Leiden University Medical Center

    Leiden, The Netherlands

    10 h-index

    45 publications

    2.3K citations

1–8 of 275

Venues

  1. The Journal of Immunology

    JI · 41 publications · 2.9K citations

    31

    h-index

  2. Journal of Biological Chemistry

    JBC · 27 publications · 1.2K citations

    23

    h-index

  3. European Journal of Immunology

    EJI · 16 publications · 968 citations

    15

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 1.5K citations

    14

    h-index

  5. The Journal of Experimental Medicine

    13 publications · 1.2K citations

    13

    h-index

1–5