Concepedia

T Cell Lineage Commitment

T Cell Lineage Commitment is a developmental decision process in which multipotent lymphoid progenitor cells undergo restriction to the T cell fate, distinguished from other hematopoietic lineages by the initiation of T cell–specific gene expression programs and the loss of alternative lineage potentials.

439

Publications

50.4K

Citations

2.7K

Authors

767

Institutions

Publications per year

2017–2026

73

Parents

Publications

439

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

, , +13

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Jason D. Fontenot, Jeffrey P. Rasmussen, Luke M. Williams et al. · Immunity · 2005 · 2.2K citations · Full text

, , +14

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

Lei Zhang, Xin Yu, Liangtao Zheng et al. · Nature · 2018 · 1.5K citations

, , +16

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

Greg M. Delgoffe, Thomas P. Kole, Yan Zheng et al. · Immunity · 2009 · 1.3K citations · Full text

, , +14

Distinct Effects of T-bet in T <sub>H</sub> 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells

Susanne J. Szabo, Brandon M. Sullivan, Claudia Stemmann et al. · Science · 2002 · 1.2K citations

, , +17

1–5 of 439

Authors

2.7K

  1. EV
    Ellen V. Rothenberg

    California Institute of Technology, United States

    23 publications · 2.4K citations

    21

    h-index

  2. JC
    Juan Carlos Zúñiga‐Pflücker

    University of Toronto, Canada

    17 publications · 3K citations

    16

    h-index

  3. HK
    Hiroshi Kawamoto

    Kyoto University, Japan

    9 publications · 1.5K citations

    9

    h-index

  4. AY
    Alexander Y. Rudensky

    Howard Hughes Medical Institute, United States

    9 publications · 6.4K citations

    9

    h-index

  5. YK
    Yoshimoto Katsura

    Kyoto University, Japan

    8 publications · 1.3K citations

    8

    h-index

1–5 of 2.7K

Institutions

767

  1. Inserm

    Paris, France

    25 h-index

    197 publications

    10.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    22 h-index

    50 publications

    14.3K citations

  3. California Institute of Technology

    Pasadena, United States

    21 h-index

    109 publications

    11K citations

  4. National Institutes of Health

    Bethesda, United States

    21 h-index

    84 publications

    13.8K citations

  5. University of Toronto

    Toronto, Canada

    19 h-index

    79 publications

    15.7K citations

  6. Harvard University

    Cambridge, United States

    19 h-index

    71 publications

    23.8K citations

  7. Sunnybrook Health Science Centre

    Toronto, Canada

    14 h-index

    42 publications

    6.6K citations

  8. University of Washington

    Seattle, United States

    13 h-index

    38 publications

    18.7K citations

1–8 of 767

Venues

  1. The Journal of Immunology

    JI · 73 publications · 4.5K citations

    41

    h-index

  2. The Journal of Experimental Medicine

    33 publications · 4.1K citations

    29

    h-index

  3. Blood

    32 publications · 2.6K citations

    25

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 26 publications · 3.1K citations

    25

    h-index

  5. Immunity

    22 publications · 7.9K citations

    22

    h-index

1–5