Concepedia

Synapse Maintenance Genes

Synapse Maintenance Genes is a theoretical construct in synaptic genetics that denotes a set of genes whose primary function is to regulate the structural and functional stability of synapses through sustained molecular signaling, protein turnover, and synaptic connectivity preservation, distinguishing it from genes primarily involved in synapse formation or elimination.

22

Publications

3K

Citations

179

Authors

79

Institutions

Publications per year

2017–2026

6

Parents

Publications

22

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

Hyo Jung Kang, Bhavya Voleti, Tibor Hajszán et al. · Nature Medicine · 2012 · 815 citations · Full text

, , +14

Systematic analysis of genes required for synapse structure and function

Derek Sieburth, Quee-Lim Ch'ng, Michael Dybbs et al. · Nature · 2005 · 406 citations

, , +14

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

Johannes B. Huppa, Michael Gleimer, Cenk Sumen et al. · Nature Immunology · 2003 · 401 citations

, , +15

The drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure

Timothy Lahey, Michael Gorczyca, X. Jia et al. · Neuron · 1994 · 305 citations · Full text

, , +14

Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2

Brad E. Pfeiffer, Tong Zang, Julia R. Wilkerson et al. · Neuron · 2010 · 151 citations · Full text

, , +15

1–5 of 22

Authors

179

  1. MD
    Michael Dybbs

    Massachusetts General Hospital, United States

    1 publications · 406 citations

    1

    h-index

  2. KI
    Kent Imaizumi

    Keio University, Japan

    1 publications · 80 citations

    1

    h-index

  3. SK
    Samir Koirala

    Harvard University, United States

    1 publications · 99 citations

    1

    h-index

  4. NH
    Namgue Hong

    Dankook University, South Korea

    1 publications · 46 citations

    1

    h-index

  5. DP
    Daniel P. Howrigan

    Broad Institute, United States

    1 publications · 66 citations

    1

    h-index

1–5 of 179

Institutions

79

  1. Harvard University

    Cambridge, United States

    4 h-index

    7 publications

    1.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    5 publications

    1.1K citations

  3. Yale University

    New Haven, United States

    2 h-index

    11 publications

    6.1K citations

  4. Stanford University

    Stanford, United States

    2 h-index

    6 publications

    1.5K citations

  5. Karolinska Institutet

    Stockholm, Sweden

    2 h-index

    7 publications

    324 citations

  6. Science for Life Laboratory

    Stockholm, Sweden

    1 h-index

    1 publications

    66 citations

  7. University of Mississippi Medical Center

    Jackson, United States

    1 h-index

    2 publications

    1.6K citations

  8. Hungarian Academy of Sciences

    Budapest, Hungary

    1 h-index

    1 publications

    815 citations

1–8 of 79

Venues

  1. Neuron

    3 publications · 602 citations

    3

    h-index

  2. Frontiers in Aging Neuroscience

    1 publications · 26 citations

    1

    h-index

  3. The Journal of Comparative Neurology

    1 publications · 20 citations

    1

    h-index

  4. Journal of Neural Transmission

    1 publications · 36 citations

    1

    h-index

  5. 1

    h-index

1–5