Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment

Xiang-Ling Meng, David Yao, Kent Imaizumi, +9

Nature

Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes

Kent Imaizumi, Takefumi Sone, Keiji Ibata, +4

Stem Cell Reports

Cerebral OrganoidSocial SciencesNeurological Disease PhenotypesNeurologyHpsc-derived Neurons +14

Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells

Keita Kajikawa, Kent Imaizumi, Munehisa Shinozaki, +10

Molecular Brain

Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function

Momotaro Kawai, Kent Imaizumi, Mitsuru Ishikawa, +16

Cell Reports

Regenerative MedicineNeuroregenerationNeurologyLocomotor FunctionNeurorehabilitation +17

Human Astrocytes Model Derived from Induced Pluripotent Stem Cells

Nicolas Leventoux, Satoru Morimoto, Kent Imaizumi, +8

Cells

Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling

Takuya Matsumoto, Koki Fujimori, Tomoko Andoh-Noda, +21

Stem Cell Reports

Induced Pluripotent Stem CellNeuroregenerationNeurological Disease ModelingMedicineNeural Stem Cell +9

The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy

Fumiko Kusunoki Nakamoto, Satoshi Okamoto, Jun Mitsui, +9

Scientific Reports

Human assembloid model of the ascending neural sensory pathway

Ji‐il Kim, Kent Imaizumi, Ovidiu F. Jurjuţ, +8

Nature

Non-viral Induction of Transgene-free iPSCs from Somatic Fibroblasts of Multiple Mammalian Species

Sho Yoshimatsu, Mayutaka Nakajima, Aozora Iguchi, +16

Stem Cell Reports

Adult Stem CellIpsc DerivationCommon MarmosetCell SpecializationRegenerative Medicine +18

Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury

Takahiro Kitagawa, Narihito Nagoshi, Yasuhiro Kamata, +13

Stem Cell Reports

Biomedical EngineeringSocial SciencesRegenerative MedicineNeuroregenerationPluripotent Stem Cells +16