Concepedia

Super-enhancer Function

Super-Enhancer Function is a genomic regulatory mechanism that belongs to the class of enhancer functions and is distinguished by its exceptional density of transcriptional coactivators and mediators, enabling robust and cell-type-specific control of gene expression programs critical for cell identity and disease.

255

Publications

31.1K

Citations

2.5K

Authors

666

Institutions

Publications per year

2017–2026

210

Parents

Publications

255

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.3K citations · Full text

, , +16

Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz, Brian J. Abraham, Tong Ihn Lee et al. · Cell · 2013 · 3.9K citations · Full text

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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

Marc R. Mansour, Brian J. Abraham, Lars Anders et al. · Science · 2014 · 818 citations · Full text

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Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma

Bjoern Chapuy, Michael R. McKeown, Charles Y. Lin et al. · Cancer Cell · 2013 · 766 citations · Full text

, , +17

Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus

Jian‐Feng Xiang, Qing-Fei Yin, Tian Chen et al. · Cell Research · 2014 · 737 citations · Full text

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1–5 of 255

Authors

2.5K

  1. RA
    Richard A. Young

    Whitehead Institute for Biomedical Research, United States

    12 publications · 3K citations

    11

    h-index

  2. BJ
    Brian J. Abraham

    Whitehead Institute for Biomedical Research, United States

    8 publications · 10.1K citations

    8

    h-index

  3. JE
    James E. Bradner

    Dana-Farber Cancer Institute, United States

    8 publications · 2.1K citations

    8

    h-index

  4. CY
    Charles Y. Lin

    Baylor College of Medicine, United States

    7 publications · 5.6K citations

    7

    h-index

  5. MW
    Michaela Willi

    National Institutes of Health, United States

    6 publications · 525 citations

    6

    h-index

1–5 of 2.5K

Institutions

666

  1. Dana-Farber Cancer Institute

    Boston, United States

    21 h-index

    122 publications

    28.7K citations

  2. Harvard University

    Cambridge, United States

    20 h-index

    136 publications

    20.5K citations

  3. National Institutes of Health

    Bethesda, United States

    16 h-index

    75 publications

    8.8K citations

  4. Sun Yat-sen University

    Guangzhou, China

    15 h-index

    144 publications

    7.3K citations

  5. Whitehead Institute for Biomedical Research

    Cambridge, United States

    13 h-index

    57 publications

    83K citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    13 h-index

    28 publications

    21.9K citations

  7. Harbin Medical University

    Harbin, China

    10 h-index

    83 publications

    7.3K citations

  8. Brigham and Women's Hospital

    Boston, United States

    9 h-index

    44 publications

    3.7K citations

1–8 of 666

Venues

  1. Nature Communications

    26 publications · 2.7K citations

    23

    h-index

  2. Nucleic Acids Research

    22 publications · 2.4K citations

    21

    h-index

  3. Cell Reports

    12 publications · 1.1K citations

    12

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 777 citations

    9

    h-index

  5. Cell

    9 publications · 9.3K citations

    9

    h-index

1–5