Structure-Activity Landscape Analysis is a computational methodology within the field of quantitative structure-activity relationship studies that characterizes the topological features of activity cliffs and discontinuities in chemical space to elucidate the relationship between molecular structural modifications and changes in biological activity.
53
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2.3K
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138
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64
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2017–2026
14
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Sala
Publications
53
Bioactivity-guided mapping and navigation of chemical space
Steffen Renner, Willem A. L. van Otterlo, Marta Domínguez et al. · Nature Chemical Biology · 2009 · 142 citations · Full text
1–5 of 53
Authors
138
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14
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8
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5
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1–5 of 138
Institutions
64
University of Bonn
Bonn, Germany
13 h-index
46 publications
2K citations
Universidad Nacional Autónoma de México
Mexico City, Mexico
11 h-index
26 publications
721 citations
Torrey Pines Institute For Molecular Studies
San Diego, United States
6 h-index
23 publications
1.8K citations
Translational Genomics Research Institute
Phoenix, United States
3 h-index
4 publications
125 citations
University of Arizona
Tucson, United States
3 h-index
4 publications
125 citations
Universidad Veracruzana
Xalapa, Mexico
2 h-index
2 publications
47 citations
National Center for Advancing Translational Sciences
Rockville, United States
2 h-index
2 publications
139 citations
Goethe University Frankfurt
Frankfurt am Main, Germany
2 h-index
4 publications
364 citations
1–8 of 64
Venues
- Journal of Chemical Information and Modeling
JCIM · 22 publications · 1K citations
17
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- Future Medicinal Chemistry
FMC · 2 publications · 52 citations
2
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- Molecular Informatics
2 publications · 63 citations
2
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- Journal of Computer-Aided Molecular Design
2 publications · 44 citations
2
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- Chemical Biology & Drug Design
2 publications · 22 citations
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