Jürgen Bajorath

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

P S Linsley, JoAnne L. Greene, William Brady et al. · Immunity · 1994 · 972 citations

Life Sciences, Immunology, Molecular Biology +15

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

Alejandro Aruffo, Mary Farrington, Diane Hollenbaugh et al. · Cell · 1993 · 824 citations

Life Sciences, Immunology, Molecular Genetics +11

Rational Development of LEA29Y (belatacept), a High-Affinity Variant of CTLA4-Ig with Potent Immunosuppressive Properties

Christian P. Larsen, Thomas C. Pearson, Andrew Adams et al. · American Journal of Transplantation · 2005 · 710 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Molecular Similarity in Medicinal Chemistry

Gerald M. Maggiora, Martin Vogt, Dagmar Stumpfe et al. · Journal of Medicinal Chemistry · 2013 · 697 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity

Gabriel Sica, In-Hak Choi, Gefeng Zhu et al. · Immunity · 2003 · 696 citations · Full text

Life Sciences, Immunology, Molecular Biology +14