Thomas C. Pearson

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

Christian P. Larsen, Eric T. Elwood, Diane Z. Alexander et al. · Nature · 1996 · 1.5K citations

Life Sciences, Cardiology, Immunology +16

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

Walter W. Shuford, Kerry Klussman, Douglas D. Tritchler et al. · The Journal of Experimental Medicine · 1997 · 792 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Rational Development of LEA29Y (belatacept), a High-Affinity Variant of CTLA4-Ig with Potent Immunosuppressive Properties

Christian P. Larsen, Thomas C. Pearson, Andrew Adams et al. · American Journal of Transplantation · 2005 · 710 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Heterologous immunity provides a potent barrier to transplantation tolerance

Andrew Adams, Matthew A. Williams, Thomas R. Jones et al. · Journal of Clinical Investigation · 2003 · 570 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +16

Phase III Study of Belatacept Versus Cyclosporine in Kidney Transplants from Extended Criteria Donors (BENEFIT‐EXT Study)

Antoine Dürrbach, JO Medina Pestana, Thomas C. Pearson et al. · American Journal of Transplantation · 2010 · 565 citations · Full text

Medicine, Nephrology, Pharmacotherapy +17