Concepedia

Stem Cell Transduction Efficiency

Stem Cell Transduction Efficiency is a quantitative metric that measures the proportion of stem cells successfully genetically modified following viral or non-viral gene delivery, distinguishing it from general transfection efficiency by specifically accounting for the unique biological and physiological barriers inherent to stem cell populations.

122

Publications

5.5K

Citations

826

Authors

265

Institutions

Publications per year

2017–2026

20

Parents

Publications

122

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G

Ramesh Akkina, R. M. Walton, Michael Chen et al. · Journal of Virology · 1996 · 321 citations · Full text

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HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G <sub>0</sub> /G <sub>1</sub> human hematopoietic stem cells

Nobuko Uchida, Richard E. Sutton, Annabelle M. Friera et al. · Proceedings of the National Academy of Sciences · 1998 · 296 citations · Full text

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Transduction of Human Progenitor Hematopoietic Stem Cells by Human Immunodeficiency Virus Type 1-Based Vectors Is Cell Cycle Dependent

Richard E. Sutton, Michael J. Reitsma, Nobuko Uchida et al. · Journal of Virology · 1999 · 196 citations · Full text

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Enhanced Transgene Expression in Cord Blood CD34+-Derived Hematopoietic Cells, Including Developing T Cells and NOD/SCID Mouse Repopulating Cells, Following Transduction with Modified TRIP Lentiviral Vectors

Aude Sirven, Emmanuel Ravet, Pierre Charneau et al. · Molecular Therapy · 2001 · 158 citations · Full text

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Critical Factors Influencing Stable Transduction of Human CD34+ Cells with HIV-1-Derived Lentiviral Vectors

Dennis L. Haas, Scott S. Case, Gay M. Crooks et al. · Molecular Therapy · 2000 · 156 citations · Full text

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1–5 of 122

Authors

826

  1. AS
    Arun Srivastava

    University of Florida, United States

    8 publications · 363 citations

    8

    h-index

  2. CL
    Chen Ling

    University of Florida, United States

    5 publications · 269 citations

    5

    h-index

  3. ZL
    Zhong Li

    Nanjing Medical University, China

    5 publications · 260 citations

    5

    h-index

  4. MC
    Mervin C. Yöder

    Indiana University – Purdue University Indianapolis, United States

    5 publications · 232 citations

    5

    h-index

  5. DB
    Donald B. Kohn

    Children's Hospital of Los Angeles, United States

    4 publications · 247 citations

    4

    h-index

1–5 of 826

Institutions

265

  1. National Institutes of Health

    Bethesda, United States

    8 h-index

    51 publications

    2.3K citations

  2. University of Florida

    Gainesville, United States

    8 h-index

    57 publications

    2.7K citations

  3. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    8 h-index

    32 publications

    1.2K citations

  4. Florida College

    Temple Terrace, United States

    8 h-index

    57 publications

    2.7K citations

  5. Indiana University School of Medicine

    Indianapolis, United States

    7 h-index

    10 publications

    380 citations

  6. Inserm

    Paris, France

    6 h-index

    30 publications

    2.3K citations

  7. National Heart Lung and Blood Institute

    Bethesda, United States

    4 h-index

    37 publications

    1.6K citations

  8. St. Jude Children's Research Hospital

    Memphis, United States

    4 h-index

    9 publications

    384 citations

1–8 of 265

Venues

  1. Human Gene Therapy

    28 publications · 1.2K citations

    21

    h-index

  2. Molecular Therapy

    13 publications · 915 citations

    12

    h-index

  3. Stem Cells

    8 publications · 314 citations

    8

    h-index

  4. PLoS ONE

    6 publications · 186 citations

    6

    h-index

  5. The Journal of Gene Medicine

    6 publications · 164 citations

    6

    h-index

1–5